Jung, Jonathan
Jonathan Jung, MD, MSc
Hometown:
Singapore
Undergraduate School:
University of Edinburgh
Graduate School:
University of Oxford
Medical School:
University of Glasgow
Bio:
Born in Singapore, I traded flip-flops for wellies to study Medical Sciences in Edinburgh, then dove into immune cells at Oxford (where I caught the medicine bug from some brilliant physician-scientists). Glasgow was next, where I fell for surgery and braved the northern chill. Love brought me to Chicago, where I swapped kilts for lab coats during a postdoc at Northwestern. Two years as a General Surgery prelim resident later, I landed at the University of Washington—finally warm, caffeinated, and in the OR where I belong. Still surgically curious, occasionally jet-lagged, and always up for a good challenge.
Personal Interests:
Lifting, canoeing, rowing, triathlon, new tech, ramen, Pho, Chelsea FC, Seattle Seahawks, Boston Celtics, Red Sox
Clinical Interests:
Transplant, Trauma, Immunology
Why UW?
The outdoors, high volume with breadth and depth of patient exposure, Seattle Seahawks
What advice do you have for incoming interns?
Remember to breath, eat and drink; have interests outside work (and I don’t mean reading academic papers in your spare time), like the Seahawks.
Publications:
1. Jung J, Hasjim BJ, Chen A, Rohan VS, Hussain F, Ladner DP & Cheung A. Early Liver Transplant for Alcohol-Associated Liver Disease: Current State and Future Directions. World Journal of Transplantation. 2025
2. Kip P, Sluiter TJ, MacArthur MR, Tao M, Jung J, Mitchell SJ, Kooijman S, Kruit N, Gorhman J, Seidman JG, Quax PHA, Aikawa M, Ozaki CK, Mitchell JR, de Vries MR. Methionine Restriction Improves Vein Graft Remodelling via PPAR-a Induced Perivascular Adipose Tissue Browning and Macrophage Polarization. Nature Communications 2024 doi: 10.1038/s41467-024-53844-8.
3. Pamulapati V, Cuda CM, Smith TL, Jung J, Xiong L, Swaminathan S, Ho KJ. Inflammatory Cell Dynamics after Murine Femoral Artery Wire Injury: A Multi-Parameter Flow Cytometry-Based Analysis. Cells. 2023. doi: 10.3390/cells12050689
4. MacArthur MR, Mitchell SJ, Chadaideh KS, Treviño-Villarreal JH, Jung J, Kalafut KC, Reynolds JS, Mann CG, Trocha KM, Tao M, Cho T-ZA, Koontanatechanon A, Yeliseyev V, Bry L, Longchamp A, Ozaki CK, Lewis CA, Carmody RN, Mitchell JR. Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization. Cell Reports. 2022. doi: 10.1016/j.celrep.2022.111187
5. Kip P, Sluiter TJ, Moore JK, Hart A, Ruske J, O’Leary J, Jung J, Tao M, MacArthur MR, Heindel P, de Jong A, de Vries MR, Burak MF, Mitchell SJ, Mitchell JR, Ozaki CK. Short-Term Pre-Operative Protein Caloric Restriction in Elective Vascular Surgery Patients: A Randomized Clinical Trial. Nutrients. 2021; doi: 0.3390/nu13114024
6. MacArthur MR, Mitchell SJ, Treviño-Villarreal JH, Grondin Y, Reynolds JS, Kip P, Jung J, Trocha KM, Ozaki CK, Mitchell JR. Total protein, not amino acid composition, differs in plant-based versus omnivorous dietary patterns and determines metabolic health effects in mice. Cell Metabolism. Jul 2021. doi: 10.1016/j.cmet.2021.06.011
7. Kip P, Tao M, Trocha KM, MacArthur MR, Peters HAB, Mitchell SJ, Mann CG, Sluiter TJ, Jung J, Patterson S, Quax PHA, de Vries MR, Mitchell JR, Ozaki CK. Periprocedural hydrogen sulfide therapy improves remodelling and attenuates vein graft disease. Journal of American Heart Association. Nov 2020. doi: 10.1161/JAHA.120.016391
8. Schwerd T, Krause F, Twigg SRF, Aschenbrenner D, Chen YH, Borgmeyer U, Müller M, Manrique S, Schumacher N, Wall SA, Jung J, Damm T, Glüer CC, Scheller J, Rose-John S, Jones EY, Laurence A, Wilkie AOM, Schmidt-Arras D, Uhlig HH. A variant in IL6ST with selective IL-11 signalling defect in human and mouse. Bone Research. Jun 2020. doi:10.1038/s41413-020-0098-z
9. Langston PK, Nambu A, Jung J, Shibata M, Aksoylar I, Lei J, Xu P, Doan MT, Jiang H, MacArthur MR, Gao X, Kong Y, Chouchani E, Locasale JW, Snyder N, Horng T. Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses. Nature Immunology. Aug 2019. doi: 10.1038/s41590-019-0453-7
10. Jung J, Zeng H, Horng T. Metabolism as a Guiding Force for Immunity. Nature Cell Biology. 2019 Jan 2. doi: 10.1038/s41556-018-0217-x. (Nature Cell Biology 20th Anniversary Invited Review Article)
11. Schwerd T, Bryant RV, Pandey S, Capitani M, Meran L, Cazier JB, Jung J, Mondal K, Parkes M, Mathew CG, Fiedler K, McCarthy DJ; WGS500 Consortium; Oxford IBD cohort study investigators; COLORS in IBD group investigators; UK IBD Genetics Consortium, Sullivan PB, Rodrigues A, Travis SPL, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J; INTERVAL Study, Russell RK, Wilson DC, Kelsen JR, Cornall R, Denson LA, Kugathasan S, Knaus UG, Serra EG, Anderson CA, Duerr RH, McGovern DP, Cho J, Powrie F, Li VS, Muise AM, Uhlig HH. NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease. Mucosal Immunol. 2017 Nov 1. doi: 10.1039/mi.2017.74
11. Schwerd T, Pandey S, Yang HT, Bagola K, Jameson E, Jung J, Lachmann RH, Shah N, Patel S, Booth C, Runz H, Düker G, Bettels R, Rohrbach M, Kugathasan S, Chapel H, Keshav S, Elkadri A, Muise AM, Koletzko S, Xavier RJ, Marquardt T, Powrie F, Wraith E, Gyrd-Hansen M, Platt F, Uhlig HH. Impaired anti-bacterial autophagy links granulomatous colitis in XIAP deficiency and Niemann-Pick disease type C1 with NOD2 variants in Crohn’s disease. Gut. 2017 March. doi: 10.1136/gutjnl-2015-310382
12. Liu KI, Ramli MN, Woo CW, Wang Y, Zhao T, Zhang X, Yim GR, Chong BY, Gowher A, Chua MZ, Jung J, Lee JH, Tan MH. A chemical-inducible CRISPR-Cas9 system for rapid control of genome editing. Nature Chemical Biology. 2016 Sep 12. doi: 10.1038/nchembio.2179. (Nature Chemical Biology Cover Article)
13. Hsieh WC, Mackinnon AC, Lu WY, Jung J, Boulter L, Henderson NC, Simpson KJ, Schotanus B, Wojtacha D, Bird TG, Medine CN, Hay DC, Sethi T, Iredale JP, Forbes SJ. Galectin-3 regulates hepatic progenitor cell expansion during liver injury. Gut. 2015 Feb;64(2):312-21. doi: 10.1136/gutjnl-2013-306290