Hovey, Liam

By Michael Hilleary | June 7, 2023

 

 

Liam Hovey, MD, PhD

Dr. Liam Hovey

Undergraduate School:

University of Iowa

Graduate School:

University of Washington

Medical School:

University of Washington

Bio:

I completed the MD-PhD program at the University of Washington, where I studied molecular adaptations to to chronic stress and worked as an organizer for the free student-run clinics providing care for the urban underserved population in Seattle. I am particularly interested in providing life-saving oncologic care, contributing to research that will improve outcomes for cancer patients, and in minimizing health disparities in cancer care outcomes.

Personal Interests:

Gardening, traveling, reading

Clinical Interests:

Surgical oncology, neuroendocrine tumors

Publications:

Surgery Education

  1. Vascular Surgery In-Training Examination performance following implementation of the Vascular Surgical Council on Resident Education curriculum. Hovey L, Quiroga E, Singh N, Zettervall S, Smith M, Abularrage CJ, Chow WB. J Vasc Surg. 2023 Apr 8:S0741-5214(23)01013-3. doi: 10.1016/j.jvs.2023.04.003. PMID: 37037260

Molecular Adaptation to Neurohormonal Stress

  1. Impairment of β-adrenergic regulation and exacerbation of pressure-induced heart failure in mice with mutations in phosphoregulatory sites in the cardiac CaV1.2 calcium channel.
    Hovey L, Guo X, Chen Y, Liu Q, Catterall WA. Front Physiol. 2023 Feb 8;14:1049611. doi: 10.3389/fphys.2023.1049611. PMID: 36846334
  2. Convergent regulation of CaV1.2 channels by direct phosphorylation and by the small GTPase RAD in the cardiac fight-or-flight response.
    Hovey L, Gamal El-Din TM, Catterall WA. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2208533119. doi: 10.1073/pnas.2208533119. Epub 2022 Oct 10. PMID: 36215501 Free PMC article.

Membrane Physiology

  1. NaV1.2 EFL domain allosterically enhances Ca2+ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD. Mahling R, Hovey L, Isbell HM, Marx DC, Miller MS, Kilpatrick AM, Weaver LD, Yoder JB, Kim EH, Andresen CNJ, Li S, Shea MA. Structure. 2021 Dec 2;29(12):1339-1356.e7. doi: 10.1016/j.str.2021.03.002. Epub 2021 Mar 25. PMID: 33770503 Free PMC article.
  2. Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1.2. Hovey L, Fowler CA, Mahling R, Lin Z, Miller MS, Marx DC, Yoder JB, Kim EH, Tefft KM, Waite BC, Feldkamp MD, Yu L, Shea MA. Biophys Chem. 2017 May;224:1-19. doi: 10.1016/j.bpc.2017.02.006. Epub 2017 Mar 9. PMID: 28343066 Free PMC article.